KIAA1524 anticorps (AA 853-903)

N° du produit ABIN7453880

L’anticorps Lapin Polyclonal anti-KIAA1524 a été validé pour WB, IP et IHC (fp). Il convient pour détecter KIAA1524 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour KIAA1524 anticorps (AA 853-903) (ABIN7453880)

Antigène: KIAA1524

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KIAA1524 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-KIAA1524 anticorps

Épitope: AA 853-903

Fonction: Rabbit anti-CIP2A Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 853 and 903

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur KIAA1524

Antigène: KIAA1524

Autre désignation: CIP2A

Sujet: Background: CIP2A (cancerous inhibitor of PP2A) was originally identified as p90, a cytoplasmic autoantigen found in the serum from a cancer patient. It was later described as a protein that interacted with the c-myc oncogene and functioned as an inhibitor of protein phosphatase 2A (PP2A) activity. Inhibition of PP2A phosphatase activity by CIP2A prevents c-myc phosphorylation and counteracts c-myc proteolytic degradation, thereby stabilizing c-myc and promoting cell growth and transformation. CIP2A is found to be overexpressed in some human malignancies and is thus classified as an oncogene that may be an important contributor to tumor formation.

ID gène: 57650

NCBI Accession: NP_065941

UniProt: Q8TCG1